The Effect of Advancing Age on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach
Abreena I. Tlumaka,
The Effect of Advancing Age on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach
Purpose: The purpose of the study was to objectively detect age-specific changes that occur in
equivalent auditory steady-state responses (ASSRs), corresponding to transient middle- and
long-latency auditory evoked potentials as a function of repetition rate and advancing age.
Method: The study included 48 normal hearing adults that were equally divided into three
groups by age: 20-39, 40-59 and 60-79 years. ASSRs were recorded at 7 repetition rates from
40 down to 0.75 Hz, elicited by trains of repeated tone-burst stimuli.
Results: Temporal analysis of middle- and long-latency equivalent ASSRs revealed no
appreciable changes in the magnitudes of the response across the age groups. Likewise, the
spectral analysis revealed that advancing age did not substantially affect the spectral content of
the response at each repetition rate. Furthermore, the harmonic sum was not significantly
different across the three age groups, between the younger-age adults versus the combined
older group sample 1 and sample 2, as well as between the two extreme age groups (i.e., 20-39
vs. 60-79) for the middle- and long-latency equivalent ASSRs.
Conclusion: Advancing age has no effect on the long-latency equivalent ASSRs; however, aging
does affect the middle-latency equivalent ASSRs when the mean age difference is ≥ 40 years.
Middle latency response (MLR)
The Effect of Advancing Age on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach
Purpose: The purpose of the study was to objectively detect age-specific changes that occur in
equivalent auditory steady-state responses (ASSRs), corresponding to transient middle- and
long-latency auditory evoked potentials as a function of repetition rate and advancing age.
Method: The study included 48 normal hearing adults that were equally divided into three
groups by age: 20-39, 40-59 and 60-79 years. ASSRs were recorded at 7 repetition rates from
40 down to 0.75 Hz, elicited by trains of repeated tone-burst stimuli.
Results: Temporal analysis of middle- and long-latency equivalent ASSRs revealed no
appreciable changes in the magnitudes of the response across the age groups. Likewise, the
spectral analysis revealed that advancing age did not substantially affect the spectral content of
the response at each repetition rate. Furthermore, the harmonic sum was not significantly
different across the three age groups, between the younger-age adults versus the combined
older group sample 1 and sample 2, as well as between the two extreme age groups (i.e., 20-39
vs. 60-79) for the middle- and long-latency equivalent ASSRs.
Conclusion: Advancing age has no effect on the long-latency equivalent ASSRs; however, aging
does affect the middle-latency equivalent ASSRs when the mean age difference is ≥ 40 years.
Middle latency response (MLR)