Altered Cortical Activity in Prelingually Deafened Cochlear Implant Users Following Long Periods of Auditory Deprivation (Record no. 2363)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02894naa a22002417a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20150123124812.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150123b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | National Acoustic Laboratory |
| 245 ## - TITLE STATEMENT | |
| Title | Altered Cortical Activity in Prelingually Deafened Cochlear Implant Users Following Long Periods of Auditory Deprivation |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc | Auditory stimulation during childhood is critical for<br/>the development of the auditory cortex in humans<br/>and with that for hearing in adulthood. Age-related<br/>changes in morphology and peak latencies of the<br/>cortical auditory evoked potential (CAEP) have led to<br/>the use of this cortical response as a biomarker of<br/>auditory cortical maturation including studies of<br/>cortical development after deafness and subsequent<br/>cochlear implantation. To date, it is unknown whether<br/>prelingually deaf adults, with early onset deafness<br/>(before the age of 2 years) and who received a<br/>cochlear implant (CI) only during adulthood, would<br/>display absent or aberrant CAEP waveforms as predicted<br/>from CAEP studies in late implanted<br/>prelingually deaf children. In the current study,<br/>CAEP waveforms were recorded in response to<br/>electric stimuli in prelingually deaf adults, who<br/>received their CI after the age of 21 years. Waveform<br/>morphology and peak latencies were compared to the<br/>CAEP responses obtained in postlingually deaf adults,<br/>who became deaf after the age of 16. Unexpectedly,<br/>typical CAEP waveforms with adult-like P1-N1-P2<br/>morphology could be recorded in the prelingually<br/>deaf adult CI users. On visual inspection, waveform<br/>morphology was comparable to the CAEP waveforms<br/>recorded in the postlingually deaf CI users.<br/>Interestingly, however, latencies of the N1 peak were<br/>significantly shorter and amplitudes were significantly<br/>larger in the prelingual group than in the postlingual <br/>group. The presence of the CAEP together with an<br/>early and large N1 peak might represent activation of<br/>the more innate and less complex components of the<br/>auditory cortex of the prelingually deaf CI user, whereas<br/>the CAEP in postlingually deaf CI users might reflect<br/>activation of the mature neural network still present in<br/>these patients. The CAEPs may therefore be helpful in<br/>the assessment of developmental state of the auditory<br/>cortex. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | cortical auditory evoked potential, |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | deafness |
| 9 (RLIN) | 513 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | cochlear implant |
| 9 (RLIN) | 1015 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | plasticity |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | auditory cortex |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | prelingual deaf |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | hearing loss |
| 9 (RLIN) | 720 |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | MARC J. W. LAMMERS,1,2 |
| 773 0# - HOST ITEM ENTRY | |
| Relationship information | 2014 |
| Title | JARO |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://dspace.nal.gov.au/xmlui/bitstream/handle/123456789/87/Altered%20cortical%20activity%20in%20%20prelingually%20deafened%20cochlear%20implant%20users%20following%20long%20periods%20of%20auditory%20deprivation.pdf?sequence=1&isAllowed=y">http://dspace.nal.gov.au/xmlui/bitstream/handle/123456789/87/Altered%20cortical%20activity%20in%20%20prelingually%20deafened%20cochlear%20implant%20users%20following%20long%20periods%20of%20auditory%20deprivation.pdf?sequence=1&isAllowed=y</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Universal Decimal Classification |
| Koha item type | Periodical publication |
No items available.