Inhibition-induced plasticity in tinnitus patients after repetitive exposure to tailor-made notched music (Record no. 2471)
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| fixed length control field | 02259nam a22001697a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20150710160723.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150710b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | National Acoustic Laboratories |
| 245 ## - TITLE STATEMENT | |
| Title | Inhibition-induced plasticity in tinnitus patients after repetitive exposure to tailor-made notched music |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc | Objective: Notch-filtered music has been shown to induce frequency-specific inhibition. Here, we investigated<br/>which cortical structures are affected by tailor-made notched music (TMNM) in tinnitus patients<br/>and how this inhibition-induced plasticity develops over time.<br/>Methods: Nine subjects suffering from chronic tonal tinnitus listened to music passing through a notchfilter<br/>centered at the patient’s individual tinnitus frequency (TMNM) for three hours on three consecutive<br/>days. Before and after each listening session, a tone at the tinnitus frequency and a control tone of 500 Hz<br/>were presented in the magnetoencephalograph. Subjective tinnitus loudness was measured via visual<br/>analog scales.<br/>Results: TMNM exposure reduced subjective tinnitus loudness and neural activity evoked by the tinnitus<br/>tone in temporal, parietal and frontal regions within the N1m time interval. Reduction of temporal and<br/>frontal activation correlated significantly with tinnitus loudness decline. Reduction of tinnitus related<br/>neural activity persisted and accumulated over three days.<br/>Conclusions: Inhibition-induced plasticity occurs in a cortical network, known to be crucial for tinnitus<br/>perception. This cortical reorganization evolves fast and accumulates across sessions.<br/>Significance: This study extends previous work on inhibition-induced plasticity, as it demonstrates the<br/>involvement of parietal and frontal areas and discovers a cumulative effect of cortical reorganization<br/>in tinnitus patients. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Auditory evoked fields (AEF) Cortical reorganization Lateral inhibition Magnetoencephalography (MEG) Auditory phantom perception Tinnitus |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | A, Stein |
| 773 0# - HOST ITEM ENTRY | |
| Relationship information | xxx (2014) xxx–xxx |
| Title | Clinical Neurophysiology |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://dspace.nal.gov.au/xmlui/bitstream/handle/123456789/215/Stein-ClinicalNeurophysiology-2014.pdf?sequence=1&isAllowed=y">http://dspace.nal.gov.au/xmlui/bitstream/handle/123456789/215/Stein-ClinicalNeurophysiology-2014.pdf?sequence=1&isAllowed=y</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Universal Decimal Classification |
| Koha item type | Journal article |
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