Deviance-Related Responses along the Auditory Hierarchy: Combined FFR, MLR and MMN Evidence (Record no. 2512)
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| 000 -LEADER | |
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| fixed length control field | 02091nam a22001577a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20151030151703.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 151030b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | National Acoustic Laboratories |
| 245 ## - TITLE STATEMENT | |
| Title | Deviance-Related Responses along the Auditory Hierarchy: Combined FFR, MLR and MMN Evidence |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc | The mismatch negativity (MMN) provides a correlate of automatic auditory discrimination in<br/>human auditory cortex that is elicited in response to violation of any acoustic regularity.<br/>Recently, deviance-related responses were found at much earlier cortical processing stages<br/>as reflected by the middle latency response (MLR) of the auditory evoked potential, and<br/>even at the level of the auditory brainstem as reflected by the frequency following response<br/>(FFR). However, no study has reported deviance-related responses in the FFR, MLR and<br/>long latency response (LLR) concurrently in a single recording protocol. Amplitude-modulated<br/>(AM) sounds were presented to healthy human participants in a frequency oddball paradigm<br/>to investigate deviance-related responses along the auditory hierarchy in the ranges<br/>of FFR, MLR and LLR. AM frequency deviants modulated the FFR, the Na and Nb components<br/>of the MLR, and the LLR eliciting the MMN. These findings demonstrate that it is possible<br/>to elicit deviance-related responses at three different levels (FFR, MLR and LLR) in one<br/>single recording protocol, highlight the involvement of the whole auditory hierarchy in deviance<br/>detection and have implications for cognitive and clinical auditory neuroscience. Moreover,<br/>the present protocol provides a new research tool into clinical neuroscience so that the<br/>functional integrity of the auditory novelty system can now be tested as a whole in a range of<br/>clinical populations where the MMN was previously shown to be defective |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tetsuya Shiga |
| 773 0# - HOST ITEM ENTRY | |
| Relationship information | September 2015 |
| Title | PLOS ONE |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://www.plosone.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pone.0136794&representation=PDF">http://www.plosone.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pone.0136794&representation=PDF</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Universal Decimal Classification |
| Koha item type | Periodical publication |
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