National Acoustic Laboratories Library

Towards an objective test of chronic tinnitus: Properties of auditory cortical potentials evoked by silent gaps in tinnitus-like sounds (Record no. 2879)

MARC details
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control field OSt
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control field 20180608141900.0
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Transcribing agency National Acoustics Laboratories
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Personal name Brandon, Paul T
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Title Towards an objective test of chronic tinnitus: Properties of auditory cortical potentials evoked by silent gaps in tinnitus-like sounds
520 3# - SUMMARY, ETC.
Summary, etc A common method designed to identify if an animal hears tinnitus assumes that tinnitus “fills-in” silent<br/>gaps in background sound. This phenomenon has not been reliably demonstrated in humans. One test of<br/>the gap-filling hypothesis would be to determine if gap-evoked cortical potentials are absent or attenuated<br/>when measured within background sound matched to the tinnitus sensation. However the tinnitus<br/>sensation is usually of low intensity and of high frequency, and it is unknown if cortical responses can be<br/>measured with such “weak” stimulus properties. Therefore the aim of the present study was to test the<br/>plausibility of observing these responses in the EEG in humans without tinnitus. Twelve non-tinnitus<br/>participants heard narrowband noises centered at sound frequencies of 5 or 10 kHz at sensation levels<br/>of either 5, 15, or 30 dB. Silent gaps of 20 ms duration were randomly inserted into noise stimuli, and<br/>cortical potentials evoked by these gaps were measured by 64-channel EEG. Gap-evoked cortical responses<br/>were statistically identifiable in all conditions for all but one participant. Responses were not<br/>significantly different between noise frequencies or levels. Results suggest that cortical responses can be<br/>measured when evoked by gaps in sounds that mirror acoustic properties of tinnitus. This design can<br/>validate the animal model and be used as a tinnitus diagnosis test in humans.
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Personal name Marc Schoenwiesner
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Personal name Sylvie Hebert
773 0# - HOST ITEM ENTRY
Relationship information April 2018
Title Hearing Research
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Uniform Resource Identifier <a href="https://dspace.nal.gov.au/xmlui/bitstream/handle/123456789/905/Towards%20an%20objective%20test%20of%20chronic%20tinnitus.pdf?sequence=1&isAllowed=y">https://dspace.nal.gov.au/xmlui/bitstream/handle/123456789/905/Towards%20an%20objective%20test%20of%20chronic%20tinnitus.pdf?sequence=1&isAllowed=y</a>
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Source of classification or shelving scheme Universal Decimal Classification
Koha item type Journal article

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